There's also Songbird.

iTunes still provides (by far) the best interface of any music management application. In typical Apple fashion, it's the small things that it's missing (chosen on purpose) that get to be infuriating sometimes. In the grand scheme of things however, the weak link in the chain, IMO, are the iPods themselves - at least the UI running on them.
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Bruno
Twisted Melon : Fine Mac OS Software